About PSMA PET/CT Imaging
Characteristics of PSMA
PSMA IS A BIOMARKER IN PROSTATE CANCER1-4
What makes PSMA an ideal target for imaging and treatment?
PSMA CHARACTERISTIC | WHAT IT MEANS | |
PSMA is overexpressed on prostate cancer (PC) cells in >80% of men with PC5-9 | Serves as an actionable biomarker, providing an accessible target for ligand binding5-9 | |
Ligands are internalized after binding with PSMA and undergo endocytic recycling2,3 | Facilitates uptake of gallium 68 in PSMA+ cells, including tumor cells2,3 | |
PSMA is not appreciably released into circulation, even in patients with progressive disease10 | Facilitates highly specific targeting of PSMA+ lesions10 |
CT, computed tomography; PET, positron emission tomography; PSMA, prostate-specific membrane antigen; PSMA+, PSMA positive.
PSMA PET Imaging in Prostate Cancer
GALLIUM Ga 68 GOZETOTIDE PSMA PET IMAGING HAS BEEN STUDIED IN MULTIPLE TRIALS AND IS APPROVED FOR PATIENTS WITH PROSTATE CANCER11-14
with suspected metastasis who are candidates for initial definitive therapy15
with suspected recurrence based on elevated serum prostate-specific antigen (PSA) level15
who are indicated for PSMA-directed therapy as described in the prescribing information of the therapeutic products15
If you're considering a PSMA PET/CT scan for your patient, find a LOCAMETZ Scanning Center near you